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Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in the Elderly with Alzheimer’s Disease (D-PRESCRIBE-AD): Trial protocol and rationale of an open-label pragmatic, prospective randomized controlled trial

Singh S, Cocoros NM, Li X, Mazor KM, Antonelli MT, Parlett L, Paullin M, Harkins TP, Zhou Y, Rochon PA, Platt R, Dashevsky I, Massino C, Saphirak C, Crawford SL, Gurwitz JH. Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in the Elderly with Alzheimer’s Disease (D-PRESCRIBE-AD): Trial protocol […]

Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in the Elderly with Alzheimer’s Disease (D-PRESCRIBE-AD): Trial protocol and rationale of an open-label pragmatic, prospective randomized controlled trial Read More »

Older adults’ attitudes towards deprescribing and medication changes: a longitudinal sub-study of a cluster randomized controlled trial

Jungo KT, Weir KR, Cateau D, Streit S. Older adults’ attitudes towards deprescribing and medication changes: a longitudinal sub-study of a cluster randomised controlled trial. BMJ Open. 2024 Jan 10;14(1):e075325. doi: 10.1136/bmjopen-2023-075325. PMID: 38199626; PMCID: PMC10806786. The study aimed to explore the link between older patients’ willingness to have medications deprescribed and the outcomes related

Older adults’ attitudes towards deprescribing and medication changes: a longitudinal sub-study of a cluster randomized controlled trial Read More »

Evaluation of a benzodiazepine deprescribing quality improvement initiative for older adults in primary care

Chae S, Lee E, Lindenberg J, Shen K, Anderson TS. Evaluation of a benzodiazepine deprescribing quality improvement initiative for older adults in primary care. J Am Geriatr Soc. 2023 Dec 26. doi: 10.1111/jgs.18728. Epub ahead of print. PMID: 38147454. This study, conducted at a large US academic medical center, aimed to evaluate the impact of

Evaluation of a benzodiazepine deprescribing quality improvement initiative for older adults in primary care Read More »

Factors Important to Older Adults Who Disagree With a Deprescribing Recommendation

Weir KR, Shang J, Choi J, Rana R, Vordenberg SE. Factors Important to Older Adults Who Disagree With a Deprescribing Recommendation. JAMA Netw Open. 2023 Oct 2;6(10):e2337281. doi: 10.1001/jamanetworkopen.2023.37281. PMID: 37819657; PMCID: PMC10568363. This investigation aimed to understand why older adults disagree with deprescribing recommendations from primary care physicians in hypothetical scenarios. The study cohort

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Ethical Aspects of Physician Decision-Making for Deprescribing Among Older Adults With Dementia

Norton JD, Zeng C, Bayliss EA, Shetterly SM, Williams N, Reeve E, Wynia MK, Green AR, Drace ML, Gleason KS, Sheehan OC, Boyd CM. Ethical Aspects of Physician Decision-Making for Deprescribing Among Older Adults With Dementia. JAMA Netw Open. 2023 Oct 2;6(10):e2336728. Deprescribing is challenging. While a number of qualitative studies have explored clinician barriers

Ethical Aspects of Physician Decision-Making for Deprescribing Among Older Adults With Dementia Read More »

Pharmacy e-Prescription Dispensing Before and After CancelRx Implementation

Pitts SI, Olson S, Yanek LR, Wang N, Woodroof T, Chen AR. Pharmacy e-Prescription Dispensing Before and After CancelRx Implementation. JAMA Intern Med. 2023;183(10):1120–1126. doi:10.1001/jamainternmed.2023.4192 The primary objective of this study was to evaluate the impact of implementing e-prescription cancellation messaging (CancelRx) on medication dispensing after e-prescription discontinuation within the electronic health record (EHR).  Pitts et al.

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Effectiveness of Bundled Hyperpolypharmacy Deprescribing Compared With Usual Care Among Older Adults – A Randomized Clinical Trial

Herrinton LJ, Lo K, Alavi M, Alexeeff SE, Butler KM, Chang C, Chang CC, Chu VL, Krishnaswami A, Deguzman LH, Prausnitz S, Mason MD, Draves M. Effectiveness of Bundled Hyperpolypharmacy Deprescribing Compared With Usual Care Among Older Adults: A Randomized Clinical Trial. JAMA Netw Open. 2023 Jul 3;6(7):e2322505. doi: 10.1001/jamanetworkopen.2023.22505. PMID: 37428504; PMCID: PMC10334220. The

Effectiveness of Bundled Hyperpolypharmacy Deprescribing Compared With Usual Care Among Older Adults – A Randomized Clinical Trial Read More »

Stakeholder Perspectives on Factors Related to Deprescribing Potentially Inappropriate Medications in Older adults Receiving Dialysis

Hall RK, Rutledge J, Lucas A, Liu CK, St Clair Russell J, St Peter W, Fish LJ, Colón-Emeric C. Stakeholder Perspectives on Factors Related to Deprescribing Potentially Inappropriate Medications in Older Adults Receiving Dialysis. Clin J Am Soc Nephrol. 2023 Jul 27. doi: 10.2215/CJN.0000000000000229. Epub ahead of print. PMID: 37499693. The study by Hall et

Stakeholder Perspectives on Factors Related to Deprescribing Potentially Inappropriate Medications in Older adults Receiving Dialysis Read More »

Medication misuse and overuse in community-dwelling persons with dementia

Deardorff WJ, Jing B, Growdon ME, Yaffe K, Boscardin WJ, Boockvar KS, Steinman MA. Medication misuse and overuse in community-dwelling persons with dementia. J Am Geriatr Soc. 2023 Jun 5. doi: 10.1111/jgs.18463. Epub ahead of print. PMID: 37272899. The study by Deardorff et al. investigated medication misuse and overuse within the community-dwelling older adult population

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Deprescribing to optimise health outcomes for frail older people: a double-blind placebo-controlled randomised controlled trial-outcomes of the Opti-med study

Etherton-Beer C, Page A, Naganathan V, Potter K, Comans T, Hilmer SN, McLachlan AJ, Lindley RI, Mangin D. Deprescribing to optimise health outcomes for frail older people: a double-blind placebo-controlled randomised controlled trial-outcomes of the Opti-med study. Age Ageing. 2023 May 1;52(5):afad081. doi: 10.1093/ageing/afad081. PMID: 37247404; PMCID: PMC10226731. The Opti-med study, conducted between 2014 and

Deprescribing to optimise health outcomes for frail older people: a double-blind placebo-controlled randomised controlled trial-outcomes of the Opti-med study Read More »

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