Raha Shahroodi

All about Outcomes: USDeN Panel Weighs in on Defining, Selecting, and Applying Deprescribing Intervention Outcomes

Bayliss, EA, Albers, K, Gleason, K, et al. Recommendations for outcome measurement for deprescribing intervention studies. J Am Geriatr Soc. 2022; 1- 11. doi:10.1111/jgs.17894 The US Deprescribing Research Network’s very own Measures Workgroup recently published recommendations for selecting and using outcomes for deprescribing interventions in the Journal of the American Geriatrics Society. Authors point to …

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How can we apply pharmacoepidemiology methods to deprescribing research questions?

Moriarty F, Thompson W, Boland F. Methods for evaluating the benefit and harms of deprescribing in observational research using routinely collected data. Res Social Adm Pharm. 2022;18(2):2269-2275. doi:10.1016/j.sapharm.2021.05.007 Recent advances in pharmacoepidemiology have allowed researchers to apply randomized controlled trial (RCT) principles to observational data. These advances have resulted in better estimates of medication harms …

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The MedSafer Study-Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial

McDonald EG, Wu PE, Rashidi B, et al. The MedSafer Study-Electronic Decision Support for Deprescribing in Hospitalized Older Adults: A Cluster Randomized Clinical Trial [published online ahead of print, 2022 Jan 18]. JAMA Intern Med. 2022;10.1001/jamainternmed.2021.7429. doi:10.1001/jamainternmed.2021.7429 A team of researchers investigated the impact of MedSafer, an electronic deprescribing tool based on electronic health record …

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Deprescribing Lessons from a Nonessential Medication Hold Policy in US Nursing Homes

 McConeghy, K. W., Cinque, M., White, E. M., Feifer, R. A., Blackman, C., Mor, V., Gravenstein, S., & Zullo, A. R. (2021). Lessons for deprescribing from a nonessential medication hold policy in US nursing homes. Journal of the American Geriatrics Society. https://doi.org/10.1111/jgs.17512   The COVID-19 pandemic caused nursing homes to rapidly adapt to new care …

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US Emergency Department Visits Attributed to Medication Harms

Budnitz DS, Shehab N, Lovegrove MC, Geller AI, Lind JN, Pollock DA. US Emergency Department Visits Attributed to Medication Harms, 2017-2019. JAMA. 2021;326(13):1299–1309. doi:10.1001/jama.2021.13844   Medication risk assessment should account for both therapeutic use as well as nontherapeutic use. Therapeutic use refers to medications taken as prescribed, while nontherapeutic use refers to unsupervised medication use, medication misuse …

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Identifying Real-World Patterns of Bisphosphonate Deprescribing in Nursing Home Residents with Dementia

Niznik, J.D., Aspinall, S.L., Hanson, L.C. et al. Patterns of Oral Bisphosphonate Deprescribing in Older Nursing Home Residents with Dementia. Osteoporos Int. Sep 2021. https://doi.org/10.1007/s00198-021-06141-9 Dr. Niznik and colleagues determines the incidence of deprescribing bisphosphonates among nursing home residents with dementia, and identified factors associated with deprescribing bisphosphonates. Dr. Niznik and team point to the …

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